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Authors: Dey, Tuli
Keywords: Anemia, goat, whole blood transfusion
Issue Date: Jun-2018
Publisher: A thesis submitted in the partial fulfillment of the requirements for the degree of Master of Science in Surgery Department of Medicine and Surgery Faculty of Veterinary Medicine Chittagong Veterinary and Animal Sciences University Chittagong-4225, Bangladesh
Abstract: The study was aimed to appraise the clinical and hematological responses of whole blood transfusion in severely anemic goat for the evaluation of feasibility of blood transfusion practice in Bangladesh. From January 2017 to September 2017, total 147 anemic goats were admitted in the Teaching Veterinary Hospital, CVASU, Bangladesh. Among them, 23 clinical anemic goats (10 for hematinic treatment and 13 for blood transfusion) of 1-2 years of age, weighing average 15 kg body weight were considered as study population. Recipients for blood transfusion were selected depending on the clinical and hematological parameters of the patients containing less than 18% PCV with clinical sign of weakness and pale or white mucous membrane. Total 13 randomly selected healthy goats were nominated as donor for blood collection in citrate phosphate dextrose adenine (CPDA-1) containing blood collecting bag that was freshly transfused to the recipient @10-12 ml/kg body weight. Clinical, haematological (TEC, HB, PCV and ESR) and biochemical (TP) parameters were evaluated before and after treatment with either hematinic drug or whole blood. In the blood transfusion group, total erythrocyte counts (TEC), packed cell volume (PCV), hemoglobin (Hb) and total protein (TP) were increased significantly (p<0.05) at 6th, 9th and 12th days of post-transfusion in comparison to pre-transfusion values. The Erythrocyte sedimentation rate (ESR) values were gradually declined significantly (p<0.01) after transfusion due to improved health condition of goats. In the hematinic group, nine patients died after treating with hematinic drug rather than blood transfusion . One patient was live among 10 after 3rd day of experiment and hemato-biochemical values were increased in that patient. Two months after treatment, all patients of blood transfusion group were recovered successfully whether nine patients were died within three days of experiment in hematinic treatment group. Therefore, it is concluded that single whole blood transfusion to severely anemic goats can be applied as a life-saving therapy to field practitioners in all over the country.
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