CARDIOPULMONARY AND POST-OPERATIVE RECOVERY NATURE OF THREE DIFFERENT ANAESTHESIA PROTOCOLS IN CATS

Abstract

General anaesthesia is often performed in cats undergoing different major or minor surgical procedures. Every anaesthetic has its own adverse effect and even the healthiest patient has also the risk of anaesthesia related complications and mortality. As a result, proper anaesthesia protocols are significant to produce balanced anaesthesia and preserve normal cardiopulmonary functions in cats. The aim of this study was to construct and evaluate three different anaesthesia protocols to assess their cardiopulmonary effects. In the study, 30 cats were divided into three groups having 10 cats in each. Drugs used as premedication- induction followed by maintenance agent were xylazine @1mg/kg- ketamine @5.45±0.49 mg/kg- halothane- fentanyl CRI in group I, dexmedetomidine @20 μg/kg- propofol @5.47 ±0.48- isoflurane- fentanyl CRI in group II and dexmedetomidine @25 μg/kg- propofol @4.52 ± 0.49- Propofol- fentanyl CRI in group III. The HR, RR, MAP decreased after premedication in every group but the alteration was minimum in dexmedetomidine premedicated cats. The sedation quality was better in dexmedetomidine in dose dependent manner than in xylazine. Both preanaesthetics resulted in reduced requirements of induction and maintenance agent. At the maintenance period HR, RR was better maintained in dexmedetomidine premedicated isoflurane-fentanyl and propofol-fentanyl anaesthesia though reduction in RR was higher than propofol-fentanyl group but halothane-fentanyl group showed halothane induced tachypnea. ETCO2 and SpO2 were well maintained in all groups. The MAP, SAP and DAP maintained better in propofol-fentanyl group than isoflurane-fentanyl and halothane-fentanyl group but the recovery was prolonged in propofol-fentanyl group.