COMPARISON OF MAINTENANCE ANESTHESIA WITH PROPOFOL AND HALOTHANE COMBINED WITH FENTANYL CRI DURING OVARIOHYSTERECTOMY IN CATS

Abstract

The study was conducted to estimate the comparison of maintenance anesthesia with propofol, and halothane combined with fentanyl CRI during ovariohysterectomy in cats admitted at Teaching Veterinary Hospital (TVH) in Chittagong Veterinary and Animal Sciences University (CVASU). Small animal anesthesia is difficult in the field condition while using proper analgesia. Propofol is a short-acting injectable anesthetic used to induce and maintain anesthesia. Halothane is the most extensively used inhaled anesthetic for general anesthesia, although it needs costly equipment and enormous amounts may cause environmental contamination. Both anesthetics lacks analgesic effect and needed multimodal approach combined with analgesic. This research investigated the anesthetic and cardiovascular effects of propofol or halothane anesthetic maintenance in cats receiving a fentanyl infusion during ovary hysterectomy, as well as the recovery from anesthesia. 18 cats were selected for ovariohysterectomy based on ASA I criteria. Propofol-fentanyl (PF) as total intravenous anesthesia (TIVA) and halothane-fentanyl (HF) as partial intravenous anesthesia (PIVA) were the two employed groups and each group had 9 cats. The cats were premedicated with xylazine hydrochloride (0.8 mg/kg), propofol (1 mg/kg, IV), and fentanyl (0.002 g/kg/h, IV) as constant-rate infusions (CRIs) in conjunction with either a CRI of propofol IV (TIVA) or halothane inhalation (PIVA). Propofol maintenance dosage was 10–11 mg/kg/hour, and end-tidal (FE'Halo) concentration of was 2-2.5 %. CRIs were started with 0.005 mg/kg fentanyl followed by 0.002 mg/kg/hour. Halothane-fentanyl was found to have lower mean arterial pressure (MAP) values at certain time intervals. While two patients in the HF group showed signs of restlessness, vocalizations, and paddling, recovery was uneventful in the PF group. Both procedures provided adequate anesthesia during surgery while having a negligible impact on cardiopulmonary function. However, the PF group takes longer than the HF group to recover from anesthesia.